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TOB1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA572533
Description
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Specifications
TOB1 | |
Polyclonal | |
Unconjugated | |
TOB1 | |
Protein Tob1; Transducer of erbB-2 1; TOB1; TOB; TROB1 | |
Rabbit | |
Protein A | |
RUO | |
10140, 22057 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
0.37 mg/mL | |
PBS with 0.09% sodium azide | |
P50616, Q61471 | |
TOB1 | |
KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human TOB1 | |
400 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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