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Invitrogen™ TOB2 Polyclonal Antibody
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Catalog No. PIPA562923
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100 μL
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PIPA562923 100 μL
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Catalog No. PIPA562923 Supplier Invitrogen™ Supplier No. PA562923
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GVASSGAGGQ QPPQQPRMAR SPTNSLLKHK SLS Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

TOB2 is a 344 amino acid rich novel member of the Tob/BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG/Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOB2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tob2
Gene Accession No. Q14106
Gene Alias 2900090N22Rik; 4930545K18Rik; APRO5; AV071822; hypothetical protein; KIAA1663; mKIAA1663; protein Tob2; Protein Tob4; Tob2; TOB4; TOBL; Transducer of erbB-2 2; transducer of ERBB2, 2; TROB2
Gene Symbols Tob2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TOB2. Recombinant protein control fragment (Product #RP-101553).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10766
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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