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Invitrogen™ TOB2 Polyclonal Antibody
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Catalog No. PIPA5110504
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100 μL
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PIPA5110504 100 μL
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Catalog No. PIPA5110504 Supplier Invitrogen™ Supplier No. PA5110504
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MQLEIKVALN FIISYLYNKL PRRRADLFGE ELERLLKKKY EGHWYPEKPL KGSGFRCVHI GEMVDPVVEL.

TOB2 is a 344 amino acid rich novel member of the Tob/BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG/Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOB2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Tob2
Gene Accession No. Q14106, Q9JM55
Gene Alias 2900090N22Rik; 4930545K18Rik; APRO5; AV071822; hypothetical protein; KIAA1663; mKIAA1663; protein Tob2; Protein Tob4; Tob2; TOB4; TOBL; Transducer of erbB-2 2; transducer of ERBB2, 2; TROB2
Gene Symbols Tob2
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10766, 315159, 57259
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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