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TOB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728871 Shop All Proteintech Group Inc Products
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50-172-8871 150 μL
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Catalog No. 50-172-8871 Supplier Proteintech Group Inc Supplier No. 136071AP150UL
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Description

Rabbit Polyclonal Antibody

TOB2 is a 344 amino acid rich novel member of the Tob/BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG/Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.

Specifications

Antigen TOB2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TOB2
Gene Accession No. Q14106, Q9JM55
Gene Alias KIAA1663, Protein Tob2, Protein Tob4, TOB2, TOB4, TOBL, Transducer of erbB 2 2, transducer of ERBB2, 2, TROB2
Gene Symbols Tob2
Host Species Rabbit
Immunogen TOB2 Fusion Protein Ag4491
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10766, 315159, 57259
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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