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Alfa Aesar™ Tolbutamide, 98%

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Quantity:
10g
50g
250g
64-77-7
C12H18N2O3S
270.347
MFCD00027169
JLRGJRBPOGGCBT-UHFFFAOYSA-N
tolbutamide,orinase,1-butyl-3-tosylurea,tolbutamid,aglicid,arkozal,artosin,diabetol,dolipol,rastinon
5505
CHEBI:27999
1-butyl-3-(4-methylphenyl)sulfonylurea
CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
64-77-7
C12H18N2O3S
270.347
MFCD00027169
JLRGJRBPOGGCBT-UHFFFAOYSA-N
tolbutamide,orinase,1-butyl-3-tosylurea,tolbutamid,aglicid,arkozal,artosin,diabetol,dolipol,rastinon
5505
CHEBI:27999
1-butyl-3-(4-methylphenyl)sulfonylurea
CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
Applications
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

Solubility
Soluble in chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Quantity 10g
Melting Point 128°C to 130°C
Beilstein 1984428
Merck Index 14,9507
Solubility Information Soluble in chloroform.
Formula Weight 270.35
Percent Purity 98%
Chemical Name or Material Tolbutamide

GHS H Statement
H302-H317
Harmful if swallowed.
May cause an allergic skin reaction.

P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c

H302-H317

EINECSNumber : 200-594-3

RTECSNumber : YS4550000

TSCA : Yes

Recommended Storage : Ambient temperatures