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Invitrogen™ TOLLIP Monoclonal Antibody (SB40a)
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Catalog No. PIMA528676
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200 μL
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PIMA528676 200 μL
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Catalog No. PIMA528676 Supplier Invitrogen™ Supplier No. MA528676
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Description

Mouse Monoclonal Antibody

TOLLIP Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOLLIP
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone SB40a
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation BBS with no preservative; pH 8.2
Gene TOLLIP
Gene Accession No. Q9H0E2, Q9QZ06
Gene Alias 4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312
Gene Symbols TOLLIP
Host Species Mouse
Immunogen Recombinant Tollip.
Purification Method Purified
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54472, 54473
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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