TOLLIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7055	Proteintech Group Inc 113151AP150UL	150 μL

Description

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Specifications

• Antigen: TOLLIP
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: A2RUW1, Q9H0E2, Q9QZ06
• Gene ID (Entrez): 361677, 54472, 54473
• Immunogen: TOLLIP Fusion Protein Ag1864
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TOLLIP

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: IL 1RAcPIP, toll interacting protein, TOLLIP
• Gene Symbols: Tollip
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody