Invitrogen™ TOMM20L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144064

Catalog No. PIPA5144064

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human SH-SY5Y whole cell, human A431 whole cell. Flow: U937 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The TOMM20L gene encodes a protein that is highly related to the translocase of outer mitochondria membrane 20 homolog (TOMM20), which plays a crucial role in the import of mitochondrial preproteins. TOMM20L, likely a paralog or isoform of TOMM20, shares functional similarities and contributes to the complex processes facilitating protein translocation across the outer mitochondrial membrane. This gene's product is integral to the translocase of the outer mitochondrial membrane (TOM) complex, which is essential for maintaining mitochondrial function and biogenesis. TOMM20L assists in the recognition and import of cytosolic precursor proteins into the mitochondria, influencing mitochondrial assembly and function. Although the specific functions of TOMM20L compared to TOMM20 require further elucidation, it is presumed to modulate mitochondrial dynamics and physiology. Alterations in TOMM20L expression could impact mitochondrial efficiency and are relevant in conditions related to energy metabolism and mitochondrial disorders.

Specifications

• Antigen: TOMM20L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOMM20L
• Gene Alias: TOMM20L; TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog type I; translocase of outer mitochondrial membrane 20 like; UNQ9438; UNQ9438/PRO34772
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387990
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q6UXN7
• Gene Symbols: TOMM20L
• Immunogen: A synthetic peptide corresponding to a sequence of human TOMM20L (EQPRELLKVFKHTLPPKVFE).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG