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Invitrogen™ TOMM22 Monoclonal Antibody (1C9-2)

Catalog No. PIMA120161
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50 μL
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Catalog No. Quantity
PIMA120161 50 μL
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Catalog No. PIMA120161 Supplier Invitrogen™ Supplier No. MA120161

Description

Mouse Monoclonal Antibody

Recommended positive controls: Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tom22 has a negatively charged N-terminal region exposed to the cytosol, a putative transmembrane region, and a C-terminal intermembrane space region with little negative charge. The following functions can be assigned to the three domains of Tom22: the cytosolic N-terminal domain plays a dual role, specifically important for presequence binding; the intermembrane space domain provides a trans binding site for presequences, and the single membrane anchor of Tom22 is crucial for the integrity of the GIP (general import gene) complex. The TOM complex of mammalian mitochondria resembles the fungal Tom complex, but is distinct from the plant TOM system. Thus, while unique components of the mammalian mitochondrial import system have been identified (e. g. TOM34 and metaxin), Tom22, and Tom37 have not been identified in plant mitochondria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOMM22
Applications Immunomicroscopy, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1C9-2
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 15mM sodium azide; pH 7.4
Gene Tomm22
Gene Accession No. Q9NS69
Gene Alias 1C9-2; 2310047D01; hTom22; Mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; MST065; MSTP065; rTOM22; Tom22; Tomm22; Translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22; translocase of outer mitochondrial membrane 22 homolog; translocase of outer mitochondrial membrane 22 homolog (yeast)
Gene Symbols Tomm22
Host Species Mouse
Immunogen Membrane fraction from Vero (monkey kidney-derived) cells.
Purification Method Purified
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56993
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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