Invitrogen™ Tomosyn Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531205

Catalog No. PIPA531205

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (98%), Rat (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Tomosyn
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STXBP5
• Gene Alias: 0710001E20Rik; 4930565N16Rik; AW742610; FLJ30922; Kiaa4253; L Nbla04300; Lethal(2) giant larvae protein homolog 3; LGL3; LLGL3; MGC141942; MGC141968; mKIAA1006; Nbla04300; putative protein product of Nbla04300; RP11-361F15.4; STXB5; Stxbp5; syntaxin binding protein 5; syntaxin binding protein 5 (tomosyn); syntaxin-binding protein 5; tomosyn; tomosyn 1; tomosyn-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 134957
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.55 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5T5C0
• Gene Symbols: STXBP5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 208 of Human Tomosyn.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG