Invitrogen™ TOP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578203

Catalog No. PIPA578203

Description

Positive Control: 293T, 293T NE Predicted Reactivity: Rat (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

Specifications

• Antigen: TOP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Top1
• Gene Alias: Ab2-086; AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; TOP1; Top-1; TOPI; topoisomerase (DNA) I; type I DNA topoisomerase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64550, 7150
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P11387, Q9WUL0
• Gene Symbols: Top1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Topoisomerase I. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG