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Invitrogen™ TOP1MT Polyclonal Antibody
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Catalog No. PA550532
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PA550532 100 μL
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Catalog No. PA550532 Supplier Invitrogen™ Supplier No. PA550532
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Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total TOP1MT protein.

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOP1MT
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TOP1MT
Gene Accession No. Q969P6
Gene Alias 2900052H09Rik; DNA topoisomerase 1, mitochondrial; DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase I; mitochondrial topoisomerase IB; TOP1M; TOP1MT; topoisomerase (DNA) I, mitochondrial; Topoisomerase I mitochondrial; Type IB Topoisomerase
Gene Symbols TOP1MT
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human topoisomerase (DNA) I, mitochondrial.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116447
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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