Invitrogen™ TOP1MT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551660

Catalog No. PIPA551660

Description

Immunogen sequence: GYCILDGHQE KIGNFKIEPP GLFRGRGDHP KMGMLKRRIT PEDVVINCSR DSKIPEPPAG HQWKEVRSDN TVTWLAAWTE SVQNSIKYIM LNPCSKLKGE TAWQKFETAR RLRGFVDEIR SQYRADWKSR EMKTRQ Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 83%.

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: TOP1MT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOP1MT
• Gene Alias: 2900052H09Rik; DNA topoisomerase 1, mitochondrial; DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase I; mitochondrial topoisomerase IB; TOP1M; TOP1MT; topoisomerase (DNA) I, mitochondrial; Topoisomerase I mitochondrial; Type IB Topoisomerase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116447
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q969P6
• Gene Symbols: TOP1MT
• Immunogen: Recombinant protein corresponding to Human TOP1MT. Recombinant protein control fragment (Product #RP-100993).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG