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Invitrogen™ TOP2A Monoclonal Antibody (A3F12)
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Catalog No. FEMA550579
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100 μL
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Catalog No. Quantity
FEMA550579 100 μL
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Catalog No. FEMA550579 Supplier Invitrogen™ Supplier No. MA550579
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Description

Mouse Monoclonal Antibody

Positive control: A549 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, human breast carcinoma tissue. Predicted band size: 174/178/182 kDa Subcellular Location: Cytoplasm, Nucleus.

Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOP2A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A3F12
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS, TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TOP2A
Gene Accession No. P11388, Q01320
Gene Alias DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A
Gene Symbols TOP2A
Host Species Mouse
Immunogen Synthetic peptide within human TOP2A aa 1480-1531.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21973, 7153
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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