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TOP2A Polyclonal Antibody, Invitrogen™

Catalog No. PIPA516322
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500 μL
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PIPA516322 500 μL
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Catalog No. PIPA516322 Supplier Thermo Scientific Supplier No. PA516322
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Description

Rabbit Polyclonal Antibody

PA5-16322 targets Topoisomerase II alpha in IF, IHC, IP, and WB applications and shows reactivity with Human samples. The PA5-16322 immunogen is a synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha.

Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOP2A
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene TOP2A
Gene Accession No. P11388
Gene Alias DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A
Gene Symbols TOP2A
Host Species Rabbit
Immunogen A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7153
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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