Invitrogen™ TOPBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596424

Catalog No. PIPA596424

Description

Immunogen sequence: KIITIEETHE ELKKQYIFQL SSLNPQERID YCHLIEKLGG LVIEKQCFDP TCTHIVVGHP LRNEKYLASV AAGKWVLHRS YLEACRTAGH FVQEEDYEWG SSSILDVLTG INVQQRRLAL AAMRWRKKIQ QRQESGIVEG AFSGWKVILH VDQSREAGFK RLLQSGGAKV LPGHSVPLFK EATHLFSDLN KLKPDDSGVN IAEAAAQNVY CLRTEYIADY LMQESPPHVE NYCLPEAISF IQNNKELGTG LSQKRKAPTE KNKIKRPRVH; Positive Samples: 293T; Cellular Location: Chromosome, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, spindle pole.

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Specifications

• Antigen: TOPBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOPBP1
• Gene Alias: 1110031N14Rik; 2810429C13Rik; AI256758; D430026L04Rik; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; KIAA0259; mKIAA0259; RGD1562949; TOP2BP1; TOPBP 1; Topbp1; topoisomerase (DNA) II beta binding protein; topoisomerase (DNA) II binding protein 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11073, 235559, 315969
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.20 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6ZQF0, Q92547
• Gene Symbols: TOPBP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_0089582).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG