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Invitrogen™ TOPORS Polyclonal Antibody
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Catalog No. PIPA5116849
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100 μL
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PIPA5116849 100 μL
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Catalog No. PIPA5116849 Supplier Invitrogen™ Supplier No. PA5116849
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver, Mouse lung, Mouse kideny, Rat kidney Immunogen sequence: PDSKCPICLD RFDNVSYLDR CLHKFCFRCV QEWSKNKAEC PLCKQPFDSI FHSVRAEDDF KEYVLRPSYN GSFTNPEVRR FRYRTTMTRE RSASLYSPSS T.

Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TOPORS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TOPORS
Gene Accession No. Q80Z37
Gene Alias AW105885; E3 ubiquitin-protein ligase Topors; LUN; p53-binding protein 3; P53BP3; p53BP3/LUN; RING-type E3 ubiquitin transferase Topors; RP31; SUMO1-protein E3 ligase Topors; TOP1 binding arginine/serine rich protein; topoisomerase 1-binding RING finger; topoisomerase I binding, arginine/serine-rich; topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase; topoisomerase I-binding arginine/serine-rich protein; Topoisomerase I-binding RING finger protein; Topors; TP53BPL; tumor suppressor p53-binding protein 3
Gene Symbols TOPORS
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse Topors (NP_5988582).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 106021, 362501
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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