TOPORS Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00629

Catalog No. 50-157-2431

Description

The recommended shelf life for this product is 1 year from date of receipt.

Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.

Specifications

• Antigen: TOPORS
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q9NS56
• Gene Symbols: TOPORS
• Immunogen: Between 995 and 1045
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunofluorescence, Immunohistochemistry
• Conjugate: Unconjugated
• Gene: TOPORS
• Gene Alias: LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10210
• Content And Storage: 4° C
• Form: Liquid