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TORC2 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501994116
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50-199-4116 100 μL
50-199-4117 10 μL
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Catalog No. 50-199-4116 Supplier Active Motif Supplier No. 39779
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Description

Rabbit Polyclonal Antibody

CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.

Specifications

Antigen TORC2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene CRTC2
Gene Accession No. Q3U182, Q53ET0
Gene Alias 4632407F12Rik; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; mTORC2; OTTHUMP00000035255; RGD1308903; Torc2; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; Transducer of regulated cAMP response element-binding protein 2
Gene Symbols CRTC2
Host Species Rabbit
Immunogen This TORC2 antibody was raised against a peptide at the C-terminus of human TORC2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 200186, 74343
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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