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TORC3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572536
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50-157-2536 10 μL
50-157-2535 100 μL
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Catalog No. 50-157-2536 Supplier Bethyl Laboratories, Inc Supplier No. IHC00684T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and Chinese ha

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predomitly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

Specifications

Antigen TORC3
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CRTC3
Gene Accession No. Q6UUV7
Gene Alias CREB-regulated transcription coactivator 3; TORC-3; transducer of CREB protein 3; transducer of regulated CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; transducer of regulated cAMP response element-binding protein 3
Gene Symbols CRTC3
Host Species Rabbit
Immunogen Between 569 and 619
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64784
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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