Invitrogen™ Torpedo californica CHRNA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117457

Catalog No. PIPA5117457

Description

This antibody has been tested in direct-ELISA.

Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine.The nAChRs fall into two subclasses, the muscle-type and the neuronal-type. The muscle-type receptor is a pentameric glycoprotein of five membrane spanning subunits, (2 alpha 1's, beta 1, gamma or epsilon and delta) which form a ligand gated ion channel. The neuronal nAChR is also a pentamer, but unlike the muscle-type, is made up of only two general types of subunits, alpha and beta of which multiple subtypes have been described (alpha 2 to alpha 8 and beta 2 to beta 4).

Specifications

• Antigen: Torpedo californica CHRNA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: acetylcholine receptor; Acetylcholine receptor subunit alpha; acetylcholine receptor, nicotinic, alpha 1 (muscle); Achr-1; ACHRA; ACHRD; Acra; AI385656; AI608266; alpha-1 subunit, nicotinic acetylcholine receptor; CHNRA; cholinergic receptor; cholinergic receptor nicotinic alpha 1 subunit; cholinergic receptor nicotinic alpha polypeptide 1; cholinergic receptor, nicotinic alpha 1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle); CHRNA; CHRNA1; CMS1A; CMS1B; CMS2A; FCCMS; muscle nicotinic acetylcholine receptor; nAChR; NACHRA1; nicotinic acetylcholine receptor alpha subunit; nicotinic acetylcholine receptor, alpha-1 subunit; nicotinic cholinergic receptor alpha 1; SCCMS
• Immunogen: Recombinant Torpedo californica Acetylcholine receptor subunit alpha protein (25-234aa).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Western Blot
• Concentration: 2.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Fish
• Product Type: Antibody
• Isotype: IgG