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Tocris Bioscience™ TP-040
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Catalog No. 777150
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Catalog No. Quantity
77-715-0 50 mg
77-711-0 10 mg
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Catalog No. 77-715-0 Supplier Tocris Bioscience™ Supplier No. 7771/50
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Potent and selective O-GlcNAcase (OGA) inhibitor

TP-040 is a potent and selective O-GlcNAcase (OGA) inhibitor (IC50 = 46 nM). It increases the level of O-GlcNAcylated protein in human neuroblastoma SH-SY5Y cells (EC50 = 450 nM). It is suitable for in vivo studies and exhibits brain permeability.

Specifications

Chemical Name or Material N-[(1-Methyl-1 H-imidazol-4-yl)methyl]-4-(4-methyl-1-piperidinyl)-2-pyrimidinamine
CAS 2757254-99-0
Quantity 50 mg
Target Hydrolase Inhibitors
Molecular Formula C15H22N6
Purity 0.98
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