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TP53BP1 Mouse anti-Human, Clone: OTI5H4, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF806952

Encompass_Preferred

Catalog No. 50-166-8049


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
Specifications

Specifications

TP53BP1
Monoclonal
Unconjugated
TP53BP1
53BP1, TDRD30, TP53, p202, p53BP1
Mouse
Affinity Chromatography
RUO
7158
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI5H4
PBS with 8% trehalose and no preservative; pH 7.3
Q12888
TP53BP1
Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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