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Invitrogen™ TP53INP2 Polyclonal Antibody
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Catalog No. PIPA5114144
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PIPA5114144 100 μL
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Catalog No. PIPA5114144 Supplier Invitrogen™ Supplier No. PA5114144
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RLQRARQRAE RHALSAKAVQ RQNRARESRP RRSKNQSSFI YQPCQRQFNY For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 86%; Dog: 79%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rat: 86%.

TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220 amino acid nuclear protein that is expressed in developing murine brain and spinal cord, as well as in the sensory and motor neuron tracts of the peripheral nervous system. A novel protein involved in the autophagy of mammalian cells, TP53INP2 translocates from the nucleus to the autophagosome structures after activation of autophagy by rapamycin or starvation. Necessary for autophagosome development and considered a scaffold protein, TP53INP2 recruits LC3 and/or LC3-related proteins, such as GABARAP and GABARAP-like2, to the autophagosome membrane by interacting with the transmembrane protein TMEM49. The gene encoding TP53INP2 is located on human chromosome 20, which is comprised of approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TP53INP2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TP53INP2
Gene Accession No. Q8IXH6
Gene Alias 1110029F20Rik; C20orf110; diabetes and obesity regulated; diabetes and obesity-regulated; Diabetes and obesity-regulated gene; Diabetes and obesity-regulated protein; dJ1181N3.1; DOR; p53-inducible protein U; PIG-U; PINH; TP53INP2; transformation related protein 53 inducible nuclear protein 2; Trp53inp2; tumor protein p53 inducible nuclear protein 2; tumor protein p53-inducible nuclear protein 2
Gene Symbols TP53INP2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C terminal region of human TP53INP2 (aa 171-220).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58476
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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