Invitrogen™ TPH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527584

Catalog No. PIPA527584

Description

Recommended positive controls: HeLa, U87-MG, SK-N-SH, IMR-32, SK-N-AS, Raw264.7, C2C12, mouse hippocampus, mouse midbrain. Predicted reactivity: Mouse (97%), Rat (99%), Zebrafish (91%), Japanese Medaka (90%), Dog (95%), Chicken (97%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Specifications

• Antigen: TPH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tph2
• Gene Alias: ADHD7; AU043594; MGC119994; Neuronal tryptophan hydroxylase; NTPH; Tph2; TPRH; TRPH; Tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; tryptophan hydroxylase 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 121278, 216343, 317675
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.3 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q8CGU9, Q8CGV2, Q8IWU9
• Gene Symbols: Tph2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 178 and 490 of Human TPH2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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