Invitrogen™ TPH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589881

Catalog No. PIPA589881

Description

Positive Samples: U-87MG, SH-SY5Y, Mouse brain, Rat brain Immunogen sequence: FDPKTTCLQE CLITTFQEAY FVSESFEEAK EKMRDFAKSI TRPFSVYFNP YTQSIEILKD TRSIENVVQD.

Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Specifications

• Antigen: TPH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tph2
• Gene Alias: ADHD7; AU043594; MGC119994; Neuronal tryptophan hydroxylase; NTPH; Tph2; TPRH; TRPH; Tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; tryptophan hydroxylase 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 121278, 216343, 317675
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.14 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q8CGU9, Q8CGV2, Q8IWU9
• Gene Symbols: Tph2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-70 of human TPH2 (NP_7754892).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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