Invitrogen™ TPM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588151

Catalog No. PIPA588151

Description

Immunogen sequence: MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE DADRKYEEVA RKLVIIESDL ERAEERAELS EGKCAELEEE LKTVTNNLKS LEAQAEKYSQ KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EDQLYQQLEQ NRRLTNELKL ALNED; Positive Samples: A-549, BT-474, THP-1, DU145, SW480, MCF7, Mouse heart, Mouse skeletal muscle, Mouse brain; Cellular Location: Cytoplasm, cytoskeleton.

Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.

Specifications

• Antigen: TPM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPM1
• Gene Alias: AA986836; AI854628; alpha tropomyosin; alpha tropomyosin of brain; alpha tropomyosin of fibroblasts F2; alpha-fTM; Alpha-tm; alpha-Tm-1; alpha-Tm-2 isoform; alpha-tropomyosin; alpha-tropomyosin (partial); alpha-tropomyosin 1; alpha-tropomyosin 2; alpha-tropomyosin of skeletal fast muscle; C15orf13; cardiac alpha tropomyosin; cardiomyopathy, hypertrophic 3; CMD1Y; CMH3; epididymis secretory protein Li 265; HEL-S-265; hepatoma alpha tropomyosin; HTM-alpha; LVNC9; sarcomeric tropomyosin kappa; smooth muscle alpha-tropomyosin; striated muscle alpha-tropomyosin; Tm1; TM2; Tm3; Tma2; Tmpa; Tmsa; Tpm1; Tpm-1; tpm1 protein; TPM1-1; TPM1-alpha; TPMA; tropomyosin; tropomyosin (CTm4); tropomyosin (CTm7); tropomyosin 1; tropomyosin 1 (alpha); tropomyosin 1 alpha chain; tropomyosin 1, alpha; tropomyosin 1-1; tropomyosin 3 alpha; tropomyosin alpha-1 chain; Tropomyosin-1; unnamed protein product; zgc:171719; zgc:55951; zgc:77009
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22003, 7168
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09493, P58771
• Gene Symbols: TPM1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human Tropomyosin 1 (NP_0010180081).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Zebrafish
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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