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Invitrogen™ TPM1 Polyclonal Antibody
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Catalog No. PIPA588151
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100 μL
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PIPA588151 100 μL
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Catalog No. PIPA588151 Supplier Invitrogen™ Supplier No. PA588151
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE DADRKYEEVA RKLVIIESDL ERAEERAELS EGKCAELEEE LKTVTNNLKS LEAQAEKYSQ KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EDQLYQQLEQ NRRLTNELKL ALNED; Positive Samples: A-549, BT-474, THP-1, DU145, SW480, MCF7, Mouse heart, Mouse skeletal muscle, Mouse brain; Cellular Location: Cytoplasm, cytoskeleton.

Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TPM1
Gene Accession No. P09493, P58771
Gene Alias AA986836; AI854628; alpha tropomyosin; alpha tropomyosin of brain; alpha tropomyosin of fibroblasts F2; alpha-fTM; Alpha-tm; alpha-Tm-1; alpha-Tm-2 isoform; alpha-tropomyosin; alpha-tropomyosin (partial); alpha-tropomyosin 1; alpha-tropomyosin 2; alpha-tropomyosin of skeletal fast muscle; C15orf13; cardiac alpha tropomyosin; cardiomyopathy, hypertrophic 3; CMD1Y; CMH3; epididymis secretory protein Li 265; HEL-S-265; hepatoma alpha tropomyosin; HTM-alpha; LVNC9; sarcomeric tropomyosin kappa; smooth muscle alpha-tropomyosin; striated muscle alpha-tropomyosin; Tm1; TM2; Tm3; Tma2; Tmpa; Tmsa; Tpm1; Tpm-1; tpm1 protein; TPM1-1; TPM1-alpha; TPMA; tropomyosin; tropomyosin (CTm4); tropomyosin (CTm7); tropomyosin 1; tropomyosin 1 (alpha); tropomyosin 1 alpha chain; tropomyosin 1, alpha; tropomyosin 1-1; tropomyosin 3 alpha; tropomyosin alpha-1 chain; Tropomyosin-1; unnamed protein product; zgc:171719; zgc:55951; zgc:77009
Gene Symbols TPM1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human Tropomyosin 1 (NP_0010180081).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22003, 7168
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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