Invitrogen™ TPM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543143

Catalog No. PIPA543143

Description

Peptide sequence: AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 85%; Human: 100%; Mouse: 100%; Pig: 85%; Rabbit: 100%; Rat: 100%; Sheep: 85%; Zebrafish: 86%.

TPM2 (tropomyosin 2) is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers. TPM2 binds to actin filaments in muscle and non-muscle cells. Plays a central role in association with the troponin complex in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis dital 1A/2B, and cap myopathy 2.

Specifications

• Antigen: TPM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPM2
• Gene Alias: AMCD1; beta tropomyosin; beta-tropomyosin; cb836; cytoskeletal protein; DA1; DA2B; epididymis secretory protein Li 273; fj63f03; HEL-S-273; NEM4; nemaline myopathy type 4; RP11-112J3.4; TMSB; TPM2; Tpm-2; tpm4l; Trop-2; tropomyosin; tropomyosin 2; tropomyosin 2 (beta); tropomyosin 2, beta; tropomyosin beta chain; Tropomyosin-2; unnamed protein product; wu:fj63f03; zgc:86810
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7169
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P07951
• Gene Symbols: TPM2
• Immunogen: Synthetic peptide directed towards the C-terminal of human TPM2 (aa 235-284).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG