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Invitrogen™ TPM2 Polyclonal Antibody
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Catalog No. PIPA591925
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100 μL
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PIPA591925 100 μL
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Catalog No. PIPA591925 Supplier Invitrogen™ Supplier No. PA591925
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Description

Rabbit Polyclonal Antibody

Positive Samples: SW620, HeLa, MCF7, U-87MG, Mouse skeletal muscle, Mouse lung; Cellular Location: Cytoplasm, cytoskeleton Immunogen sequence: MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKEAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD.

TPM2 (tropomyosin 2) is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers. TPM2 binds to actin filaments in muscle and non-muscle cells. Plays a central role in association with the troponin complex in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis dital 1A/2B, and cap myopathy 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM2
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TPM2
Gene Accession No. P07951, P58774, P58775
Gene Alias AMCD1; beta tropomyosin; beta-tropomyosin; cb836; cytoskeletal protein; DA1; DA2B; epididymis secretory protein Li 273; fj63f03; HEL-S-273; NEM4; nemaline myopathy type 4; RP11-112J3.4; TMSB; TPM2; Tpm-2; tpm4l; Trop-2; tropomyosin; tropomyosin 2; tropomyosin 2 (beta); tropomyosin 2, beta; tropomyosin beta chain; Tropomyosin-2; unnamed protein product; wu:fj63f03; zgc:86810
Gene Symbols TPM2
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22004, 500450, 7169
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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