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Invitrogen™ TPM3 Polyclonal Antibody
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Catalog No. PIPA552644
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100 μL
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PIPA552644 100 μL
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Catalog No. PIPA552644 Supplier Invitrogen™ Supplier No. PA552644
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AERLQREVEG ERRAREQAEA EVASLNRRIQ LVEEELDRAQ ERLATALQKL EEAEKAADES ERGMKVIENR ALKDEEKMEL QEIQLKEAKH IAEEADRKYE EVARKLVIIE GDLERTEERA ELAESRCREM DEQIRLMDQN LKCLSA Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

TPM3 (tropomyosin 3) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TPM3
Gene Accession No. P06753, P21107, Q63610
Gene Alias alpha-tropomyosin, slow skeletal; CAPM1; CFTD; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; gamma-TM; gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; HEL-189; HEL-S-82p; hscp30; hTM30nm; hTM5; hTMnm; NEM1; nonmuscle tropomyosin 5; OK/SW-cl.5; skalphaTM.2; TM3; TM30; TM30nm; TM5; TM-5; Tm5NM; TMnm; TPM3; Tpm5; Tpm-5; TPMsk3; TRK; Trop-5; tropomyosin; tropomyosin 3; tropomyosin 3, gamma; tropomyosin 5; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin non-muscle; tropomyosin-3; Tropomyosin-5
Gene Symbols TPM3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TPM3. Recombinant protein control fragment (Product #RP-89192).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117557, 59069, 7170
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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