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Invitrogen™ TPM3 Polyclonal Antibody
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Catalog No. PIPA529770
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100 μL
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PIPA529770 100 μL
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Catalog No. PIPA529770 Supplier Invitrogen™ Supplier No. PA529770
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (80%), Dog (89%), Pig (100%), Rhesus Monkey (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TPM3 (tropomyosin 3) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.44 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene TPM3
Gene Accession No. P06753, P21107
Gene Alias alpha-tropomyosin, slow skeletal; CAPM1; CFTD; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; gamma-TM; gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; HEL-189; HEL-S-82p; hscp30; hTM30nm; hTM5; hTMnm; NEM1; nonmuscle tropomyosin 5; OK/SW-cl.5; skalphaTM.2; TM3; TM30; TM30nm; TM5; TM-5; Tm5NM; TMnm; TPM3; Tpm5; Tpm-5; TPMsk3; TRK; Trop-5; tropomyosin; tropomyosin 3; tropomyosin 3, gamma; tropomyosin 5; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin non-muscle; tropomyosin-3; Tropomyosin-5
Gene Symbols TPM3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Tropomyosin 3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 59069, 7170
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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