Invitrogen™ TPM4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 720311

Catalog No. PI720311

Description

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Pig, Horse and Rat.

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: TPM4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPM4
• Gene Alias: 2610528G24Rik; epididymis secretory protein Li 108; HEL-S-108; TM30p1; TM-4; TPM4; Tpm4.2; Tpm4.2cy; tropomycin 4; tropomyosin; tropomyosin 4; tropomyosin alpha-4 chain; Tropomyosin-4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 326618, 7171
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P67936, Q6IRU2
• Gene Symbols: TPM4
• Immunogen: Peptides corresponding to Human TPM4 (aa 21-34, 229-244).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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