Invitrogen™ TPM4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592152

Catalog No. PIPA592152

Description

Immunogen sequence: MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI; Positive Samples: Mouse lung, Rat heart; Cellular Location: Cytoplasm, cytoskeleton.

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: TPM4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPM4
• Gene Alias: 2610528G24Rik; epididymis secretory protein Li 108; HEL-S-108; TM30p1; TM-4; TPM4; Tpm4.2; Tpm4.2cy; tropomycin 4; tropomyosin; tropomyosin 4; tropomyosin alpha-4 chain; Tropomyosin-4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24852, 326618
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09495, Q6IRU2
• Gene Symbols: TPM4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human TPM4 (NP_0032811).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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