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Invitrogen™ TPM4 Polyclonal Antibody
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Catalog No. PIPA592152
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100 μL
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PIPA592152 100 μL
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Catalog No. PIPA592152 Supplier Invitrogen™ Supplier No. PA592152
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI; Positive Samples: Mouse lung, Rat heart; Cellular Location: Cytoplasm, cytoskeleton.

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TPM4
Gene Accession No. P09495, Q6IRU2
Gene Alias 2610528G24Rik; epididymis secretory protein Li 108; HEL-S-108; TM30p1; TM-4; TPM4; Tpm4.2; Tpm4.2cy; tropomycin 4; tropomyosin; tropomyosin 4; tropomyosin alpha-4 chain; Tropomyosin-4
Gene Symbols TPM4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human TPM4 (NP_0032811).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24852, 326618
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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