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Invitrogen™ TPM4 Polyclonal Antibody
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Catalog No. PIPA5143162
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100 μg
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Catalog No. Quantity
PIPA5143162 100 μg
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Catalog No. PIPA5143162 Supplier Invitrogen™ Supplier No. PA5143162
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001138632.1; NP_003281.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPM4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TPM4
Gene Accession No. P67936, P67937, Q6IRU2
Gene Alias 2610528G24Rik; epididymis secretory protein Li 108; HEL-S-108; TM30p1; TM-4; TPM4; Tpm4.2; Tpm4.2cy; tropomycin 4; tropomyosin; tropomyosin 4; tropomyosin alpha-4 chain; Tropomyosin-4
Gene Symbols TPM4
Host Species Goat
Immunogen Peptide with sequence C-ENVGLHQTLDQ (aa 230-240).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 326618, 397608, 7171
Target Species Human, Mouse, Pig
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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