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TPP1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988623
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100 μL
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50-198-8623 100 μL
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Catalog No. 50-198-8623 Supplier Bioss Supplier No. BS8528R
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Rabbit Polyclonal Antibody

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Specifications

Antigen TPP1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TPP1
Gene Accession No. O14773
Gene Alias Cell growth-inhibiting gene 1 protein; ceroid-lipofuscinosis, neuronal 2; CLN 2; Cln2; GIG 1; GIG1; growth-inhibiting protein 1; LPIC; lysosomal pepstatin insensitive protease; Lysosomal pepstatin-insensitive protease; MGC21297; SCAR7; TPP 1; TPP I; TPP1; TPP-1; TPPI; TPP-I; Tripeptidyl aminopeptidase; tripeptidyl peptidase 1; tripeptidyl peptidase I; tripeptidyl peptidase-I; Tripeptidyl-peptidase 1; Tripeptidyl-peptidase I; UNQ267/PRO304
Gene Symbols TPP1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TPP1/CLN2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1200
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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