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Invitrogen™ TPRKB Monoclonal Antibody (3F6)
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Catalog No. PIMA521843
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100 μg
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Catalog No. Quantity
PIMA521843 100 μg
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Catalog No. PIMA521843 Supplier Invitrogen™ Supplier No. MA521843
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Description

Mouse Monoclonal Antibody

Peptide Sequence: KLGKMKTRTL STEIIFNLSP NNNISEALKK FGISANDTSI LIVYIEEGEK QINQEYLISQ VEGHQVSLKN LPEIMNITEV KKIYKLSSQE ESIGTLLDAI ICRMSTKDVL.

TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPRKB
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3F6
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene TPRKB
Gene Accession No. Q9Y3C4
Gene Alias 0610033G21Rik; 1810034M08Rik; CGI121; Cgi-121; DRWMS1; EKC/KEOPS complex subunit TPRKB; mDRWMS1; My019; Prpk (p53-related protein kinase)-binding protein; PRPK-binding protein; RGD1309786; Tp53rk binding protein; TP53RK-binding protein; TP53RK-binding protein; EKC/KEOPS complex subunit TPRKB; TPRKB; WBSCR18; zgc:101896
Gene Symbols TPRKB
Host Species Mouse
Immunogen TPRKB (NP_057142, 66 a.a. ~ 175 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51002
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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