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Invitrogen™ TPRKB Polyclonal Antibody
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Catalog No. PIPA521792
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100 μL
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PIPA521792 100 μL
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Catalog No. PIPA521792 Supplier Invitrogen™ Supplier No. PA521792
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Mouse (83%), Rat (82%), Pig (90%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPRKB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene TPRKB
Gene Accession No. Q9Y3C4
Gene Alias 0610033G21Rik; 1810034M08Rik; CGI121; Cgi-121; DRWMS1; EKC/KEOPS complex subunit TPRKB; mDRWMS1; My019; Prpk (p53-related protein kinase)-binding protein; PRPK-binding protein; RGD1309786; Tp53rk binding protein; TP53RK-binding protein; TP53RK-binding protein; EKC/KEOPS complex subunit TPRKB; TPRKB; WBSCR18; zgc:101896
Gene Symbols TPRKB
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human TPRKB. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51002
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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