TPRKB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 128001AP150UL

Catalog No. 50-172-8260

Description

This antibody is a rabbit polyclonal antibody raised against full length TPRKB of human origin.

TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.

Specifications

• Antigen: TPRKB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPRKB
• Gene Alias: CGI 121, My019, PRPK binding protein, TP53RK binding protein, TPRKB
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 297411, 51002, 69786
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q5PQR8, Q8QZZ7, Q9Y3C4
• Gene Symbols: TPRKB
• Immunogen: TPRKB Fusion Protein Ag3551
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG