Invitrogen™ TPSD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559094

Catalog No. PIPA559094

Description

Immunogen sequence: NVHLPPPYPL KEVEVPVVEN HLCNAEYHTG LHTGHSFQIV RD Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 62%.

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.

Specifications

• Antigen: TPSD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TPSD1
• Gene Alias: Delta-tryptase; hmMCP-3-like tryptase III; Mast cell mMCP-7-like; mast cell tryptase; MCP7L1; MCP7-LIKE; MMCP-7L; mMCP-7-like delta II tryptase; mMCP-7-like-1; mMCP-7-like-2; TPSD1; Tryptase delta; tryptase delta 1; tryptase-3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23430
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BZJ3
• Gene Symbols: TPSD1
• Immunogen: Recombinant protein corresponding to Human TPSD1. Recombinant protein control fragment (Product #RP-98352).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov