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Invitrogen™ TPSD1 Polyclonal Antibody
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Catalog No. PIPA562007
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PIPA562007 100 μL
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Catalog No. PIPA562007 Supplier Invitrogen™ Supplier No. PA562007
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KDLAALRVQL REQHLYYQDQ LLPVSRIIV Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 59%.

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPSD1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TPSD1
Gene Accession No. Q9BZJ3
Gene Alias Delta-tryptase; hmMCP-3-like tryptase III; Mast cell mMCP-7-like; mast cell tryptase; MCP7L1; MCP7-LIKE; MMCP-7L; mMCP-7-like delta II tryptase; mMCP-7-like-1; mMCP-7-like-2; TPSD1; Tryptase delta; tryptase delta 1; tryptase-3
Gene Symbols TPSD1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TPSD1. Recombinant protein control fragment (Product #RP-104454).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23430
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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