Invitrogen™ TPT1 Recombinant Rabbit Monoclonal Antibody (10A9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538315

Catalog No. PIMA538315

Description

This antibody has been tested in direct-ELISA.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.

Specifications

• Antigen: TPT1
• Classification: Recombinant Monoclonal
• Concentration: 0.16 mg/mL
• Formulation: PBS with 50% glycerol, 150mM NaCl and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P13693, P63028
• Gene Symbols: TPT1
• Immunogen: A synthesized peptide derived from human TCTP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 10A9
• Conjugate: Unconjugated
• Gene: TPT1
• Gene Alias: 21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22070, 7178
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid