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  6. TPT1 Mouse anti-Human, Mouse, Rat, Clone: 1G6A10, Proteintech 

TPT1 Mouse anti-Human, Mouse, Rat, Clone: 1G6A10, Proteintech
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Catalog No. 501737128 Shop All Proteintech Group Inc Products
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50-173-7128 150 μL
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Catalog No. 50-173-7128 Supplier Proteintech Group Inc Supplier No. 667131IG150UL
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Description

Mouse Monoclonal Antibody

This antibody detected 22 kDa TPT1 in lysates.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer′s disease and Down syndrome.

Specifications

Antigen TPT1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1G6A10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TPT1
Gene Accession No. P13693, P63028, P63029
Gene Alias FLJ27337, Fortilin, Histamine releasing factor, HRF, p02, p23, TCTP, TPT1
Gene Symbols TPT1
Host Species Mouse
Immunogen TPT1 Fusion Protein Ag27651
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116646, 22070, 7178
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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