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Invitrogen™ TPT1 Polyclonal Antibody
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Catalog No. PIPA5111108
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PIPA5111108 100 μL
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Catalog No. PIPA5111108 Supplier Invitrogen™ Supplier No. PA5111108
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MIIYRDLISH DEMFSDIYKI REIADGLCLE VEGKMVSRTE GNIDDSLIGG NASAEGPEGE GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYM Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPT1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TPT1
Gene Accession No. P13693
Gene Alias 21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
Gene Symbols TPT1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human TPT1. Recombinant protein control fragment (Product #RP-102871).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7178
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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