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Invitrogen™ TPT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586377

Catalog No. PIPA586377


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Description

Description

Purity is > 95% by SDS-PAGE.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TPT1
Polyclonal
Unconjugated
TPT1
21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
Rabbit
Antigen affinity chromatography
RUO
116646, 22070, 7178
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P13693, P63028, P63029
TPT1
Synthetic peptide, corresponding to amino acids 70-120 of Human HRF.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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