TRA-1-81 Antigen Mouse anti-Human, PE, Clone: TRA-1-81, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 560161
The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.
Host Species: Mouse
Isotype: IgM, κ
Species Reactivity: Human
Immunogen: Human Embryonal Carcinoma Cell Line
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Human Embryonal Carcinoma Cell Line|
For Research Use Only.