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TRA-1-81 Antigen Mouse anti-Human, PE, Clone: TRA-1-81, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 560885

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Catalog No. BDB560885


Description

Description

The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.

Specifications

Specifications

TRA-1-81 Antigen
TRA-1-81
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse
IgM, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE
Affinity Purified
Human Embryonal Carcinoma Cell Line
25 Tests
Cell Biology
Primary
Human
SDS
Documents
Product Certifications
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