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Invitrogen™ TRAC-1 Polyclonal Antibody
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Catalog No. PIPA559607
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100 μL
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PIPA559607 100 μL
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Catalog No. PIPA559607 Supplier Invitrogen™ Supplier No. PA559607
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CIATSLKNNK WTCPYCRAYL PSEGVPATDV AKRMKSEYKN CAECDTLVCL SEMRAHIRTC QKYIDKYGPL QELEETAARC VCP Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 88%.

TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRAC-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF125
Gene Accession No. Q96EQ8
Gene Alias 4930553F04Rik; E3 ubiquitin-protein ligase RNF125; RING finger protein 125; ring finger protein 125, E3 ubiquitin protein ligase; RNF125; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TNORS; TRAC1; TRAC-1
Gene Symbols RNF125
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TRAC-1. Recombinant protein control fragment (Product #RP-98228).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54941
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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