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TRADD Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501730251 Shop All Proteintech Group Inc Products
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50-173-0251 150 μL
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Catalog No. 50-173-0251 Supplier Proteintech Group Inc Supplier No. 154681AP150UL
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Description

Rabbit Polyclonal Antibody

TRADD′s nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Specifications

Antigen TRADD
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TRADD
Gene Accession No. Q15628, Q3U0V2
Gene Alias Hs.89862, TRADD
Gene Symbols Tradd
Host Species Rabbit
Immunogen TRADD Fusion Protein Ag7768
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 71609, 8717
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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