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Invitrogen™ TRAF1 Polyclonal Antibody
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Catalog No. PIPA5105281
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100 μL
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PIPA5105281 100 μL
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Catalog No. PIPA5105281 Supplier Invitrogen™ Supplier No. PA5105281
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TRAF1.

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRAF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TRAF1
Gene Accession No. P39428, Q13077
Gene Alias 4732496E14Rik; EBI6; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; TNF receptor associated factor 1; TNF receptor-associated factor 1; Traf1
Gene Symbols TRAF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TRAF1(Accession Q13077), corresponding to amino acid residues Q372-T416.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22029, 687813, 7185
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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