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TRAF3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
$518.60
Specifications
Antigen | TRAF3 |
---|---|
Concentration | 0.42 mg/mL |
Applications | Flow Cytometry, Immunoprecipitation, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-173-1985
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Proteintech Group Inc
180991AP150UL |
150 μL |
Each of 1 for $518.60
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Description
Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g. RANK, CD30, CD40, etc.) and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1-TRAF6). TRAF3, originally named CRAF1, interacts directly with the CD40 cytoplasmic tail through a region of similarity to the tumor necrosis factor-alpha (TNF-alpha) receptor-associated factors. TRAF3 binds only a single site, which contains the sequence PEQET, whereas TRAF1 and TRAF2 are capable of binding to either the PEQET site or an additional downstream domain.Specifications
TRAF3 | |
Flow Cytometry, Immunoprecipitation, Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
Q13114 | |
7187 | |
TRAF3 Fusion Protein Ag12185 | |
Primary | |
-20°C | |
TRAF3 |
0.42 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
CAP 1, CAP1, CD40 binding protein, CD40bp, CRAF1, LAP1, LMP1 associated protein 1, TRAF3 | |
TRAF3 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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